Distinct serum biosignatures are associated with different tuberculosis treatment outcomes

Author:

Ronacher Katharina,Chegou Novel N.,Kleynhans Léanie,Djoba Siawaya Joel F.,du Plessis Nelita,Loxton André G.,Maasdorp Elizna,Tromp Gerard,Kidd Martin,Stanley Kim,Kriel Magdalena,Menezes Angela,Gutschmidt Andrea,van der Spuy Gian D.,Warren Robin M.,Dietze Reynaldo,Okwera Alphonse,Thiel Bonnie,Belisle John T.,Cliff Jacqueline M.,Boom W. Henry,Johnson John L.,van Helden Paul D.,Dockrell Hazel M.,Walzl Gerhard

Funder

Bill and Melinda Gates Foundation

EDCTP

South African Technology for Human Resources and Industry Program

Case Western Reserve University

National Institute of Allergy and Infectious Diseases, National Institutes of Health

International Collaborations in Infectious Diseases Research

National Institute of Allergy and Infectious Diseases

South African government

South African Medical Research Council

Strategic Health Innovations Partnership

National Research Foundation

South African Research Chair Initiative: Biomarkers for TB

Publisher

Elsevier BV

Subject

Infectious Diseases,Microbiology (medical),Immunology,Microbiology

Reference25 articles.

1. A controlled trial of a 2-month, 3-month, and 12-month regimens of chemotherapy for sputum smear-negative pulmonary tuberculosis: the results at 30 months. Hong Kong Chest Service/Tuberculosis Research Centre, Madras/British Medical Research Council;Hong Kong Chest Service/Tuberculosis Research Center Madras/British Medical Research;Am Rev Respir Dis,1981

2. A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis;Imperial;Nat Med,2018

3. Assessment of new sterilizing drugs for treating pulmonary tuberculosis by culture at 2 months;Mitchison;Am Rev Respir Dis,1993

4. Biomarkers for tuberculosis disease activity, cure, and relapse;Wallis;Lancet Infect Dis,2010

5. Month 2 culture status and treatment duration as predictors of tuberculosis relapse risk in a meta-regression model;Wallis;PLoS One,2013

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