Multiple responses optimization in the development of a headspace gas chromatography method for the determination of residual solvents in pharmaceuticals

Author:

Teglia Carla M.,Montemurro Milagros,De Zan María M.,Cámara María S.

Funder

Universidad Nacional del Litoral

ANPCyT (Agencia Nacional de Promoción Científica y Tecnológica

Publisher

Elsevier BV

Subject

Analytical Chemistry,Electrochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Pharmacy

Reference29 articles.

1. Static headspace gas chromatographic method for the determination of low and high boiling residual solvents in betamethasone valerate;Somuramasami;J. Pharm. Biomed. Anal.,2011

2. Evaluation of the European pharmacopoeia method for control of residual solvents in some antibiotics;Sitaramaraju;J. Pharm. Biomed. Anal.,2008

3. Analysis of organic volatile impurities in pharmaceutical excipients by static headspace capillary gas chromatography;Fliszar;J. Chromatogr. A,2004

4. Proceedings of International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH), Tripartite Harmonised Guideline Q3C (R5), Impurities: Guideline for Residual Solvents, 2011.

5. Basic Gas Chromatography;Mcnair,2009

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