Epidemiological study on Fournier syndrome in a tertiary hospital in Jundiaí-SP from October 2016 to October 2018†

Author:

Inácio Mariana Fernandes1ORCID,Lima Renato Pierre1,Neto Sebastião Rizzo1,Lopes Felipe Andrade2,Pantaroto Mário1,de Sousa Alexandre Venâncio3

Affiliation:

1. Faculdade de Medicina de Jundiaí, São Paulo, SP, Brazil

2. Hospital São Vicente de Paulo Jundiaí, São Paulo, SP, Brazil

3. Faculdade de Medicina de Jundiaí, Programa de Residência de Cirurgia Geral, São Paulo, SP, Brazil

Abstract

Abstract Introduction Fournier’s gangrene is a polymicrobial infection caused by aerobic and anaerobic microorganisms, which determine a fast and progressive necrotizing fasciitis, compromising mainly the perineal region and the genital region, being able to evolve to sepsis, multiple organ failure and death. Treatment consists of early surgical diagnosis and debridement, associated with broad-spectrum antibiotic therapy and hyperbaric oxygen therapy. Objective Compare the most prevalent epidemiological data of patients with Fournier's Syndrome with the data examined in the literature in order to evaluate the incidence in the analyzed service, treatment form and evolution of the patients with the disease. Materials and methods Observational transversal study from the medical records of patients diagnosed with the disease at the São Vicente de Paulo Charity Hospital in Jundiaí, SP, from October 2016 to October 2018. Results 23 patients with Fournier’s Syndrome, all included in the study, and were analyzed. The most prevalent epidemiological data on the disease, such as age, sex, association with other comorbidities, treatment performed, mortality and early surgical procedure, had obtained a similar data as compared as the medical literature that was in studied. Conclusion Despite the recognized severity of Fournier’s Syndrome, early diagnosis combined with extensive surgical debridement, broad-spectrum antibiotic therapy and measures and oxygen therapy when available are important measures to contain the rapid progression of the disease, thus decreasing its levels of mortality.

Funder

Own Financing

Publisher

Georg Thieme Verlag KG

Subject

Gastroenterology

Reference10 articles.

1. Fournier’s gangrene;Smith;Br J Urol,1998

2. Management of Fournier ́s gangrene: an eleven year retrospective analysis of early recognition, diagnosis, and treatment;Norton;Am Surg,2002

3. Outcome prediction in patients with Fournier ́s gangrene;Laor;J Urol,1995

4. Manejo da gangrena de Fournier: experiência de um hospital universitário de Curitiba;Mehl;Rev Col Bras Cir,2010

5. Prognostic factors in Fournier gangrene;Jeong;Int J Urol,2005

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