Molecular basis for thymidine modulation of the efficacy and toxicity of alkylating agents

Author:

Hwu Wen-Jen Poo,Mozdziesz Diane E.

Publisher

Elsevier BV

Subject

Pharmacology (medical),Pharmacology

Reference79 articles.

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3. Chlorozotocin, 2-[3-(2-chloroethyl)-3-nitrosoureido]-d-glucopyranose, an antitumor agent with modified bone marrow toxicity;Anderson;Cancer Res.,1975

4. Effect of thymidine on uptake, DNA alkylation, and DNA repair in L1210 cells treated with 1,3-bis(2-chloroethyl)-1-nitrosourea or 3′-[3-(2-chloroethyl)-3-nitrosoureido]-3′-deoxythymidine;August;Cancer Res.,1988

5. Inhibition of poly (adenosine diphosphate-ribose) polymerase by thymidine and thymidine analogues in L1210 cells, and its relationship to the potentiation of the antitumor activity of 1,3-bis(2-chloroethyl)-1-nitrosourea but not of 3′-[3-(2-chloroethyl)-3-nitrosoureido]-3′-deoxythymidine;August;Cancer Res.,1991

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