Molecular cloning and functional identification of sterol C24-methyltransferase gene from Tripterygium wilfordii

Author:

Guan Hongyu,Zhao Yujun,Su Ping,Tong Yuru,Liu Yujia,Hu Tianyuan,Zhang Yifeng,Zhang Xianan,Li Jia,Wu Xiaoyi,Huang Luqi,Gao Wei

Funder

National Natural Science Foundation of China

Beijing Municipal Universities

Key project at Central Government Level: The Ability Establishment of Sustainable Use for Valuable Chinese Medicine Resources

Publisher

Elsevier BV

Subject

General Pharmacology, Toxicology and Pharmaceutics

Reference30 articles.

1. Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae);Brinker;Phytochemistry,2007

2. XPB, a subunit of TFIIH, is a target of the natural product triptolide;Titov;Nat Chem Biol,2011

3. Natural product triptolide mediates cancer cell death by triggering CDK7-dependent degradation of RNA polymerase II;Manzo;Cancer Res,2012

4. A preclinical evaluation of minnelide as a therapeutic agent against pancreatic cancer;Chugh;Sci Transl Med,2012

5. Cloning and protein expression of sterol-C-24-methyl transferase 2 in Tripterygium wilfordii;Guan;Acta Pharm Sin,2016

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