Design, synthesis, molecular modeling, and biological evaluation of acrylamide derivatives as potent inhibitors of human dihydroorotate dehydrogenase for the treatment of rheumatoid arthritis-Reference-Cited by-同舟云学术

Design, synthesis, molecular modeling, and biological evaluation of acrylamide derivatives as potent inhibitors of human dihydroorotate dehydrogenase for the treatment of rheumatoid arthritis

Published:2021-03 Issue:3 Volume:11 Page:795-809
ISSN:2211-3835
Container-title:Acta Pharmaceutica Sinica B
language:en
Short-container-title:Acta Pharmaceutica Sinica B

Author:

Zeng Fanxun,Li Shiliang^ORCID,Yang Guantian,Luo Yating,Qi Tiantian,Liang Yingfan,Yang Tingyuan,Zhang Letian,Wang Rui,Zhu Lili,Li Honglin,Xu Xiaoyong

Funder

National Key Research and Development Program

National Natural Science Foundation of China

National Science & Technology Major Project “Key New Drug Creation and Manufacturing Program”

Fundamental Research Funds for the Central Universities

Shanghai Foundation of Science and Technology

Shanghai Sailing Program

National Program for Special Supports of Eminent Professionals

National Program for Support of Top-Notch Young Professionals

Publisher

Elsevier BV

Subject

General Pharmacology, Toxicology and Pharmaceutics

Reference62 articles.

1. Immunopathogenesis of rheumatoid arthritis;Firestein;Immunity,2017

2. 2010 Rheumatoid arthritis classification criteria: an American college of rheumatology/European League against rheumatism collaborative initiative;Aletaha;Arthritis Rheum,2010

3. Evolving concepts of rheumatoid arthritis;Firestein;Nature,2003

4. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: Part I;Helmick;Arthritis Rheum,2008

5. Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study;McInnes;Ann Rheum Dis,2015

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