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The substitution of SERCA2 redox cysteine 674 promotes pulmonary vascular remodeling by activating IRE1α/XBP1s pathway

  • Published:2022-05 Issue:5 Volume:12 Page:2315-2329
  • ISSN:2211-3835
  • Container-title:Acta Pharmaceutica Sinica B
  • language:en
  • Short-container-title:Acta Pharmaceutica Sinica B

Author:

Yu Weimin,Xu Gang,Chen Hui,Xiao Li,Liu Gang,Hu Pingping,Li Siqi,Kasim ViviORCID,Zeng Chunyu,Tong XiaoyongORCID

Funder

National Natural Science Foundation of China

Natural Science Foundation of Chongqing

Fundamental Research Funds for the Central Universities

Chongqing Research Program of Basic Research and Frontier Technology

Publisher

Elsevier BV

Subject

General Pharmacology, Toxicology and Pharmaceutics

Reference48 articles.

1. Updated clinical classification of pulmonary hypertension;Simonneau;J Am Coll Cardiol,2013

2. Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure;Stenmark;Am J Physiol Lung Cell Mol Physiol,2009

3. Haemodynamic definitions and updated clinical classification of pulmonary hypertension;Simonneau;Eur Respir J,2019

4. Pulmonary vascular disease and pulmonary hypertension;Ghigna;Diagn Histopathol,2019

5. Animal models of pulmonary hypertension: matching disease mechanisms to etiology of the human disease;Michael;J Pulm Respir Med,2014

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