Optimization of a doxycycline hydroxypropyl-β-cyclodextrin inclusion complex based on computational modeling

Author:

Wang Zhouhua,He Zixin,Zhang Lei,Zhang Haohao,Zhang Meimei,Wen Xinguo,Quan Guilan,Huang Xintian,Pan Xin,Wu Chuanbin

Funder

National Natural Science Foundation of China

National Science & Technology Pillar Program

International Cooperation and Exchange Program of China

Publisher

Elsevier BV

Subject

General Pharmacology, Toxicology and Pharmaceutics

Reference33 articles.

1. Novel compaction techniques with pellet-containing granules;Pan;Eur J Pharm Biopharm,2010

2. The effect of doxycycline temperature-sensitive hydrogel on inhibiting the corneal neovascularization induced by BFGF in rats;Su;Graefes Arch Clin Exp Ophthalmol,2011

3. Use of cyclodextrins in topical formulations: practical aspects;Cal;Eur J Pharm Biopharm,2008

4. deVries T, Gold L. Inventors. Warner Chilcott Company, Inc., assignee. Doxycycline metal complex in a solid dosage form. US patent US2005/0019396-A1; 2005 Jan 27.

5. Doxycycline and hydroxypropyl-β-cyclodextrin complex in poloxamer thermal sensitive hydrogel for ophthalmic delivery;He;Acta Pharm Sin B,2011

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