A brief history of the discovery of PXR and CAR as xenobiotic receptors
Author:
Funder
Joseph Koslow Endowed Professorship from the University of Pittsburgh School of Pharmacy
Publisher
Elsevier BV
Subject
General Pharmacology, Toxicology and Pharmaceutics
Reference23 articles.
1. An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway;Kliewer;Cell,1998
2. SXR, a novel steroid and xenobiotic-sensing nuclear receptor;Blumberg;Genes Dev,1998
3. BXR, an embryonic orphan nuclear receptor activated by a novel class of endogenous benzoate metabolites;Blumberg;Genes Dev,1998
4. Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit hepatocytes;Barwick;Mol Pharmacol,1996
5. A novel cis-acting element in a liver cytochrome P450 3A gene confers synergistic induction by glucocorticoids plus antiglucocorticoids;Quattrochi;J Biol Chem,1995
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