Nobiletin and its derivatives overcome multidrug resistance (MDR) in cancer: total synthesis and discovery of potent MDR reversal agents

Author:

Feng Senling,Zhou Huifang,Wu Deyan,Zheng Dechong,Qu Biao,Liu Ruiming,Zhang Chen,Li Zhe,Xie Ying,Luo Hai-Bin

Funder

National Key R&D Program of China

Macao Science and Technology Development Fund

National Natural Science Foundation of China

Guangdong Province Higher Vocational Colleges & Schools Pearl River Scholar Funded Scheme

Publisher

Elsevier BV

Subject

General Pharmacology, Toxicology and Pharmaceutics

Reference22 articles.

1. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries;Bray;CA: Cancer J Clin,2018

2. Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp;Alfarouk;Cancer Cell Int,2015

3. Optimization of cancer treatment through overcoming drug resistance;Elshimali;J Cancer Res Oncobiol,2018

4. Inhibition of the multidrug resistance p-glycoprotein: time for a change of strategy?.;Callaghan;Drug Metab Dispos,2014

5. Secalonic acid D induces cell apoptosis in both sensitive and ABCG2-overexpressing multidrug resistant cancer cells through upregulating c-Jun expression;Zhang;Acta Pharm Sin B,2019

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