PXR variants: the impact on drug metabolism and therapeutic responses-Reference-Cited by-同舟云学术

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PXR variants: the impact on drug metabolism and therapeutic responses

Published:2016-09 Issue:5 Volume:6 Page:441-449
ISSN:2211-3835
Container-title:Acta Pharmaceutica Sinica B
language:en
Short-container-title:Acta Pharmaceutica Sinica B

Author:

Brewer C. Trent,Chen Taosheng

Funder

American Lebanese Syrian Associated Charities

St. Jude Children′s Research Hospital

U.S. National Institutes of Health

Publisher

Elsevier BV

Subject

General Pharmacology, Toxicology and Pharmaceutics

Reference85 articles.

1. Coactivator binding promotes the specific interaction between ligand and the pregnane X receptor;Watkins;J Mol Biol,2003

2. Nuclear receptors as drug targets in cholestasis and drug-induced hepatotoxicity;Zollner;Pharmacol Ther,2010

3. An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway;Kliewer;Cell,1998

4. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions;Lehmann;J Clin Invest,1998

5. Nuclear receptor drug discovery;Chen;Curr Opin Chem Biol,2008

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