Crosstalk of HNF4 α with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipids

Author:

Lu Hong

Funder

U.S. National Institute of Health (NIH)

Publisher

Elsevier BV

Subject

General Pharmacology, Toxicology and Pharmaceutics

Reference214 articles.

1. Mammalian hepatocyte differentiation requires the transcription factor HNF-4α;Li;Genes Dev,2000

2. Plasticity and expanding complexity of the hepatic transcription factor network during liver development;Kyrmizi;Genes Dev,2006

3. Hepatocyte nuclear factor 4α (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis;Hayhurst;Mol Cell Biol,2001

4. Regulation of hepatocyte nuclear factor 4α-mediated transcription;Gonzalez;Drug Metab Pharmacokinet,2008

5. HNF4α—role in drug metabolism and potential drug target?;Hwang-Verslues;Curr Opin Pharmacol,2010

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