Loss of extra-striatal phosphodiesterase 10A expression in early premanifest Huntington's disease gene carriers
Author:
Publisher
Elsevier BV
Subject
Neurology (clinical),Neurology
Reference45 articles.
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2. Altered PDE10A expression detectable early before symptomatic onset in Huntington's disease;Niccolini;Brain,2015
3. The phosphodiesterase 10 positron emission tomography tracer, F-18 MNI-659, as a novel biomarker for early Huntington disease;Russell;JAMA Neurol.,2014
4. PET imaging shows loss of striatal PDE10A in patients with Huntington disease;Ahmad;Neurology,2014
5. PDE10 inhibition increases GluA1 and CREB phosphorylation and improves spatial and recognition memories in a Huntington's disease mouse model;Giralt;Hippocampus,2013
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1. Neuroimaging to Facilitate Clinical Trials in Huntington’s Disease: Current Opinion from the EHDN Imaging Working Group;Journal of Huntington's Disease;2024-07-02
2. Inhibition of phosphodiesterase 10A by MP-10 rescues behavioral deficits and normalizes microglial morphology and synaptic pruning in a mouse model of FOXP1 syndrome;2024-03-05
3. Emerging phosphodiesterase inhibitors for treatment of neurodegenerative diseases;Medicinal Research Reviews;2024-01-27
4. Prediction of molecular interaction of Phosphodiesterase 10A inhibition by natural compounds: insights from structure-based screening and molecular dynamics simulations;Journal of Biomolecular Structure and Dynamics;2023-10-18
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