Wearing-off symptoms during standard and extended natalizumab dosing intervals: Experiences from the COVID-19 pandemic

Author:

Bringeland Gerd Haga,Blaser Nello,Myhr Kjell-Morten,Vedeler Christian Alexander,Gavasso Sonia

Publisher

Elsevier BV

Subject

Neurology (clinical),Neurology

Reference8 articles.

1. A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis;Polman;N. Engl. J. Med.,2006

2. Multiple sclerosis symptom recrudescence at the end of the natalizumab dosing cycle;Ratchford;Int. J. MS Care,2014

3. The natalizumab wearing-off effect: end of natalizumab cycle; recurrence of MS symptoms;van Kempen;Neurology,2019

4. Wearing-off at the end of natalizumab dosing intervals is associated with low receptor occupancy;Bringeland;Neurol. Neuroimmunol. Neuroinflamm.,2020

5. Monitoring CD49d receptor occupancy: a method to optimize and personalize natalizumab therapy in multiple sclerosis patients;Punet-Ortiz;Cytometry B Clin. Cytom.,2017

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