Genetic Risk Underlying Psychiatric and Cognitive Symptoms in Huntington’s Disease
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Published:2020-05
Issue:9
Volume:87
Page:857-865
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ISSN:0006-3223
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Container-title:Biological Psychiatry
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language:en
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Short-container-title:Biological Psychiatry
Author:
Ellis Natalie, Tee Amelia, McAllister Branduff, Massey Thomas, McLauchlan Duncan, Stone Timothy, Correia Kevin, Loupe Jacob, Kim Kyung-Hee, Barker Douglas, Hong Eun PyoORCID, Chao Michael J., Long Jeffrey D.ORCID, Lucente Diane, Vonsattel Jean Paul G., Pinto Ricardo MouroORCID, Elneel Kawther Abu, Ramos Eliana Marisa, Mysore Jayalakshmi Srinidhi, Gillis Tammy, Wheeler Vanessa C., Medway Christopher, Hall LynseyORCID, Kwak Seung, Sampaio Cristina, Ciosi MarcORCID, Maxwell Alastair, Chatzi Afroditi, Monckton Darren G.ORCID, Orth Michael, Landwehrmeyer G. Bernhard, Paulsen Jane S., Shoulson Ira, Myers Richard H., van Duijn ErikORCID, Rickards Hugh, MacDonald Marcy E., Lee Jong-min, Gusella James F., Jones Lesley, Holmans PeterORCID
Funder
CHDI Foundation National Institutes of Health Medical Research Council
Subject
Biological Psychiatry
Reference47 articles.
1. Huntington disease;Bates;Nat Rev Dis Prim,2015 2. Neuropsychiatry and neuropsychology;Craufurd,2014 3. Identification of genetic factors that modify clinical onset of Huntington’s disease;Cell,2015 4. Genetic modifiers of Mendelian disease: Huntington’s disease and the trinucleotide repeat disorders;Holmans;Hum Mol Genet,2017 5. Huntington’s disease onset is determined by length of uninterrupted CAG, not encoded polyglutamine, and is modified by DNA maintenance mechanisms;Lee;bioRxiv,2019
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