Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use

Author:

Brazel David M.,Jiang Yu,Hughey Jordan M.,Turcot Valérie,Zhan Xiaowei,Gong Jian,Batini ChiaraORCID,Weissenkampen J. Dylan,Liu MengZhenORCID,Barnes Daniel R.,Bertelsen Sarah,Chou Yi-Ling,Erzurumluoglu A. MesutORCID,Faul Jessica D.,Haessler Jeff,Hammerschlag Anke R.,Hsu Chris,Kapoor Manav,Lai Dongbing,Le Nhung,de Leeuw Christiaan A.,Loukola Anu,Mangino Massimo,Melbourne Carl A.,Pistis GiorgioORCID,Qaiser Beenish,Rohde Rebecca,Shao Yaming,Stringham HeatherORCID,Wetherill LeahORCID,Zhao Wei,Agrawal Arpana,Bierut Laura,Chen Chu,Eaton Charles B.,Goate Alison,Haiman Christopher,Heath Andrew,Iacono William G.,Martin Nicholas G.,Polderman Tinca J.,Reiner Alex,Rice JohnORCID,Schlessinger David,Scholte H. Steven,Smith Jennifer A.,Tardif Jean-Claude,Tindle Hilary A.,van der Leij Andries R.,Boehnke MichaelORCID,Chang-Claude Jenny,Cucca Francesco,David Sean P.,Foroud Tatiana,Howson Joanna M.M.,Kardia Sharon L.R.,Kooperberg Charles,Laakso Markku,Lettre Guillaume,Madden Pamela,McGue Matt,North Kari,Posthuma Danielle,Spector Timothy,Stram Daniel,Tobin Martin D.,Weir David R.,Kaprio JaakkoORCID,Abecasis Gonçalo R.,Liu Dajiang J.,Vrieze Scott,Surendran Praveen,Young Robin,Barnes Daniel R.,Nielsen Sune Fallgaard,Rasheed Asif,Samuel Maria,Zhao Wei,Kontto Jukka,Perola Markus,Caslake Muriel,de Craen Anton J.M.,Trompet Stella,Uria-Nickelsen Maria,Malarstig Anders,Reily Dermot F.,Hoek Maarten,Vogt Thomas,Jukema J. Wouter,Sattar Naveed,Ford Ian,Packard Chris J.,Alam Dewan S.,Majumder Abdulla al Shafi,Di Angelantonio Emanuele,Chowdhury Rajiv,Amouyel Philippe,Arveiler Dominique,Blankenberg Stefan,Ferrières Jean,Kee Frank,Kuulasmaa Kari,Müller-Nurasyid Martina,Veronesi Giovanni,Virtamo Jarmo,EPIC-CVD Consortium ,Frossard Philippe,Nordestgaard Børge Grønne,Saleheen Danish,Danesh John,Butterworth Adam S.,Howson Joanna M.M.,Erzurumluoglu A. Mesut,Jackson Victoria E.,Melbourne Carl A.,Varga Tibor V.,Warren Helen R.,Tragante Vinicius,Tachmazidou Ioanna,Harris Sarah E.,Evangelou Evangelos,Marten Jonathan,Zhang Weihua,Altmaier Elisabeth,Luan Jian’an,Langenberg Claudia,Scott Robert A.,Yaghootkar Hanieh,Stirrups Kathleen,Kanoni Stavroula,Marouli Eirini,Karpe Fredrik,Dominiczak Anna F.,Sever Peter,Poulter Neil,Rolandsson Olov,Baumbach Clemens,Afaq Saima,Chambers John C.,Kooner Jaspal S.,Wareham Nicholas J.,Renström Frida,Hallmans Göran,Marioni Riccardo E.,Corley Janie,Starr John M.,Verweij Niek,de Boer Rudolf A.,van der Meer Peter,Yavas Ersin,Vaartjes Ilonca,Bots Michiel L.,Asselbergs Folkert W.,Grabe Hans J.,Völzke Henry,Nauck Matthias,Weiss Stefan,Pharoah Paul D.P.,Dunning Alison M.,Dennis Joe G.,Thompson Deborah J.,Michailidou Kyriaki,Easton Douglas F.,Antoniou Antonis C.,Tyrrell Jessica,Mihailov Evelin,Samani Nilesh J.,Zhou Kaixin,Neville Matthew J.,Metspalu Andres,Palmer Colin N.A.,Hall Ian P.,Strachan David P.,Deary Ian J.,Frayling Tim M.,Hayward Caroline,van der Harst Pim,Zeggini Eleftheria,Understanding Society Scientific Group ,Munroe Patricia B.,Jansson Jan-Håkan,Franks Paul W.,Deloukas Panos,Caulfield Mark J.,Wain Louise V.,Tobin Martin D.

Funder

National Institute on Drug Abuse

National Human Genome Research Institute of the National Institutes of Health

National Science Foundation

National Science Foundation Graduate Research Fellowship Program

European Union Innovative Medicines Initiative

Pfizer

Publisher

Elsevier BV

Subject

Biological Psychiatry

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