An Unbiased Drug Screen for Seizure Suppressors in Duplication 15q Syndrome Reveals 5-HT1A and Dopamine Pathway Activation as Potential Therapies-Reference-Cited by-同舟云学术

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An Unbiased Drug Screen for Seizure Suppressors in Duplication 15q Syndrome Reveals 5-HT1A and Dopamine Pathway Activation as Potential Therapies

Published:2020-11 Issue:9 Volume:88 Page:698-709
ISSN:0006-3223
Container-title:Biological Psychiatry
language:en
Short-container-title:Biological Psychiatry

Author:

Roy Bidisha,Han Jungsoo^ORCID,Hope Kevin A.,Peters Tracy L.^ORCID,Palmer Glen,Reiter Lawrence T.^ORCID

Funder

University of Tennessee Health Science Center

National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health and Human Development

Dup15q Alliance

Publisher

Elsevier BV

Subject

Biological Psychiatry

Reference87 articles.

1. 15q duplication syndrome and related disorders;Finucane,1993

2. Behavioral characterization of dup15q syndrome: Toward meaningful endpoints for clinical trials;DiStefano;Am J Med Genet A,2020

3. The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology;Dindot;Hum Mol Genet,2008

4. Allelic specificity of Ube3a expression in the mouse brain during postnatal development;Judson;J Comp Neurol,2014

5. Regulation of the large (similar to 1000 kb) imprinted murine Ube3a antisense transcript by alternative exons upstream of Snurf/Snrpn;Landers;Nucleic Acids Res,2004

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