A step closer to continuous buffer preparation from solids: Predicting powder compaction and how to prevent it

Author:

Komuczki D.,Hesse N.,Schmidt J.,Satzer P.

Publisher

Elsevier BV

Subject

Molecular Biology,General Medicine,Bioengineering,Biotechnology

Reference25 articles.

1. Buffer capacity of biologics–from buffer salts to buffering by antibodies;Karow;Biotechnol Prog,2013

2. Impact of buffers on colloidal property and aggregation propensities of a bispecific antibody;Majumder;J Pharm Sci,2019

3. Impact of buffer, protein concentration and sucrose addition on the aggregation and particle formation during freezing and thawing;Hauptmann;Pharm Res,2018

4. Economics and ecology: modelling of continuous primary recovery and capture scenarios for recombinant antibody production;Cataldo;J Biotechnol,2020

5. Gibson K, Vengsarkar P, de Vilmorin P, Sinclair A, Carlson C, Attig S, et al. An economic evaluation of buffer preparation philosophies for the biopharmaceutical industry; 2019.

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