Evidence for an actin binding helix in gelsolin segment 2; have homologous sequences in segments 1 and 2 of gelsolin evolved to divergent actin binding functions?-Reference-Cited by-同舟云学术

Evidence for an actin binding helix in gelsolin segment 2; have homologous sequences in segments 1 and 2 of gelsolin evolved to divergent actin binding functions?

Published:1996-11-18 Issue:2-3 Volume:397 Page:191-196
ISSN:0014-5793
Container-title:FEBS Letters
language:en
Short-container-title:

Author:

Van Troys M.,Dewitte D.,Goethals M.,Vandekerckhove J.,Ampe C.

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1016/S0014-5793(96)01086-1/fullpdf

Reference30 articles.

1. Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain

2. Modulation of gelsolin function by phosphatidylinositol 4,5-bisphosphate

3. F-actin capping proteins

4. Gelsolin has three actin-binding sites.

5. Expression of human plasma gelsolin in Escherichia coli and dissection of actin binding sites by segmental deletion mutagenesis.

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