Stat5a sobers up inTOXicated T cells
Author:
Funder
German Research Foundation
Publisher
Elsevier BV
Subject
Infectious Diseases,Immunology,Immunology and Allergy
Reference11 articles.
1. ‘Stem-like’ precursors are the fount to sustain persistent CD8(+) T cell responses;Zehn;Nat. Immunol.,2022
2. Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade;Pauken;Science,2016
3. Stat5 opposes the transcription factor tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure;Beltra;Immunity,2023
4. TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection;Alfei;Nature,2019
5. TOX transcriptionally and epigenetically programs CD8(+) T cell exhaustion;Khan;Nature,2019
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