A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure-Reference-Cited by-同舟云学术

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A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure

Published:2017-04 Issue:4 Volume:46 Page:690-702
ISSN:1074-7613
Container-title:Immunity
language:en
Short-container-title:Immunity

Author:

Lee Jeong Hyun,Andrabi Raiees,Su Ching-Yao,Yasmeen Anila,Julien Jean-Philippe,Kong Leopold,Wu Nicholas C.,McBride Ryan,Sok Devin,Pauthner Matthias,Cottrell Christopher A.,Nieusma Travis,Blattner Claudia,Paulson James C.,Klasse Per Johan,Wilson Ian A.,Burton Dennis R.,Ward Andrew B.

Funder

California HIV/AIDS Research Program Dissertation Award

Scripps CHAVI-ID

International AIDS Vaccine Initiative

Bill and Melinda Gates Foundation CAVD

National Cancer Institute

National Institute of General Medical Sciences

DOE Office of Science

Publisher

Elsevier BV

Subject

Infectious Diseases,Immunology,Immunology and Allergy

Reference51 articles.

1. PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr., Sect: D Biol;Adams;Crystallogr.,2010

2. Identification of common features in prototype broadly neutralizing antibodies to HIV envelope V2 apex to facilitate vaccine design;Andrabi;Immunity,2015

3. EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy;Barad;Nat. Methods,2015

4. Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers;Blattner;Immunity,2014

5. Broadly neutralizing antibodies to HIV and their role in vaccine design;Burton;Annu. Rev. Immunol.,2016

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