Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rβ1-Reference-Cited by-同舟云学术

Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rβ1

Published:2018-01 Issue:1 Volume:48 Page:45-58.e6
ISSN:1074-7613
Container-title:Immunity
language:en
Short-container-title:Immunity

Author:

Bloch Yehudi,Bouchareychas Laura,Merceron Romain,Składanowska Katarzyna,Van den Bossche Lien,Detry Sammy,Govindarajan Srinath,Elewaut Dirk,Haerynck Filomeen,Dullaers Melissa,Adamopoulos Iannis E.,Savvides Savvas N.

Funder

Flanders Agency for Innovation and Entrepreneurship

Research Foundation Flanders

Ghent University Hospital Spearhead Initiative for Immunology Research

Jeffrey Modell Foundation

NIAMS/NIH

National Psoriasis Foundation Translational Research Grant

Hercules Foundation

VIB

Publisher

Elsevier BV

Subject

Infectious Diseases,Immunology,Immunology and Allergy

Reference74 articles.

1. PHENIX: a comprehensive Python-based system for macromolecular structure solution;Adams;Acta Crystallogr. D Biol. Crystallogr.,2010

2. Therapeutic efficacy of interleukin 12/interleukin 23 blockade in generalized pustular psoriasis regardless of IL36RN mutation status;Arakawa;JAMA Dermatol.,2016

3. A time- and cost-efficient system for high-level protein production in mammalian cells;Aricescu;Acta Crystallogr. D Biol. Crystallogr.,2006

4. Therapeutic targeting of the IL-12/23 pathways: generation and characterization of ustekinumab;Benson;Nat. Biotechnol.,2011

5. Crystal structures of the pro-inflammatory cytokine interleukin-23 and its complex with a high-affinity neutralizing antibody;Beyer;J. Mol. Biol.,2008

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