An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus

Author:

Snijder Joost,Ortego Michael S.,Weidle Connor,Stuart Andrew B.,Gray Matthew D.,McElrath M. Juliana,Pancera Marie,Veesler David,McGuire Andrew T.

Funder

Vaccine and Infectious Disease Division Faculty Initiative Grant “EBV Vaccine Discovery” through the Fred Hutchinson Cancer Research Center

National Institute of General Medical Sciences (NIGMS) of the National Institutes of Health

Seattle Structural and Genomics Center for Infectious Disease from the National Institute of Allergy and Infectious Diseases

Pew Biomedical Scholars Award

Netherlands Organization for Scientific Research (NWO

European Molecular Biology Organisation (EMBO

NIH

NSF

CNSI at UCLA

National Institutes of Health, National Institute of General Medical Sciences

Director, Office of Science, Office of Basic Energy Sciences, of the U.S. Department of Energy

University of Washington’s Proteomics Resource

Publisher

Elsevier BV

Subject

Infectious Diseases,Immunology,Immunology and Allergy

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3. Structure of a trimeric variant of the Epstein-Barr virus glycoprotein B;Backovic;Proc. Natl. Acad. Sci. USA,2009

4. Antigenic cross-reactions among herpes simplex virus types 1 and 2, Epstein-Barr virus, and cytomegalovirus;Balachandran;J. Virol.,1987

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