Signals of pseudo-starvation unveil the amino acid transporter SLC7A11 as key determinant in the control of Treg cell proliferative potential

Author:

Procaccini Claudio,Garavelli SilviaORCID,Carbone Fortunata,Di Silvestre Dario,La Rocca Claudia,Greco DarioORCID,Colamatteo Alessandra,Lepore Maria Teresa,Russo Claudia,De Rosa Giusy,Faicchia Deriggio,Prattichizzo FrancescoORCID,Grossi Sarah,Campomenosi PaolaORCID,Buttari Fabio,Mauri PierluigiORCID,Uccelli AntonioORCID,Salvetti Marco,Brescia Morra Vincenzo,Vella DanilaORCID,Galgani Mario,Mottola Maria,Zuccarelli Bruno,Lanzillo Roberta,Maniscalco Giorgia Teresa,Centonze Diego,de Candia PaolaORCID,Matarese GiuseppeORCID

Funder

MIUR

National Multiple Sclerosis Society

JDRF

Ministero della Salute

Fondazione Italiana Sclerosi Multipla

Publisher

Elsevier BV

Subject

Infectious Diseases,Immunology,Immunology and Allergy

Reference81 articles.

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3. AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis;Becher;Dev. Cell,2018

4. Effectiveness of delayed-release dimethyl fumarate on patient-reported outcomes and clinical measures in patients with relapsing-remitting multiple sclerosis in a real-world clinical setting: PROTEC;Berger;Mult. Scler. J. Exp. Transl. Clin.,2019

5. Regulatory T cell proliferative potential is impaired in human autoimmune disease;Carbone;Nat. Med.,2014

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