Loss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint Blockade Therapy in Metastatic Uterine Leiomyosarcoma

Author:

George Suzanne,Miao Diana,Demetri George D.,Adeegbe Dennis,Rodig Scott J.,Shukla Sachet,Lipschitz Mikel,Amin-Mansour Ali,Raut Chandrajit P.,Carter Scott L.,Hammerman Peter,Freeman Gordon J.,Wu Catherine J.,Ott Patrick A.,Wong Kwok-Kin,Van Allen Eliezer M.

Funder

BroadIgnite

BroadNext10

Catherine England Leiomyosarcoma Research Fund

Ludwig Center at Harvard

Erica Kaitz LMS RESEARCH NOW Fund

NIH

Alexandra J. Miliotis Pediatric Oncology Research Fund

Howard Hughes Medical Institute Medical Research Fellowship

Publisher

Elsevier BV

Subject

Infectious Diseases,Immunology,Immunology and Allergy

Reference39 articles.

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3. Genomic characterization of brain metastases reveals branched evolution and potential therapeutic targets;Brastianos;Cancer Discov.,2015

4. The somatic genomic landscape of glioblastoma;Brennan;Cell,2013

5. Absolute quantification of somatic DNA alterations in human cancer;Carter;Nat. Biotechnol.,2012

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