The cytokine Meteorin-like inhibits anti-tumor CD8+ T cell responses by disrupting mitochondrial function

Author:

Jackson Christopher M.ORCID,Pant Ayush,Dinalankara Wikum,Choi John,Jain Aanchal,Nitta Ryan,Yazigi Eli,Saleh Laura,Zhao Liang,Nirschl Thomas R.,Kochel Christina M.,Hwa-Lin Bergsneider Brandon,Routkevitch Denis,Patel Kisha,Cho Kwang Bog,Tzeng Stephany,Neshat Sarah Y.,Kim Young-Hoon,Smith Barbara J.,Ramello Maria Cecilia,Sotillo Elena,Wang Xinnan,Green Jordan J.,Bettegowda Chetan,Li Gordon,Brem Henry,Mackall Crystal L.,Pardoll Drew M.,Drake Charles G.,Marchionni Luigi,Lim Michael

Funder

Janssen Scientific Affairs

Bristol-Myers Squibb

NIH

Publisher

Elsevier BV

Reference62 articles.

1. CD8+ T cell metabolism in infection and cancer;Reina-Campos;Nat. Rev. Immunol.,2021

2. Subfatin is a novel adipokine and unlike Meteorin in adipose and brain expression;Li;CNS Neurosci. Ther.,2014

3. Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis;Rao;Cell,2014

4. METRNL attenuates lipid-induced inflammation and insulin resistance via AMPK or PPARδ-dependent pathways in skeletal muscle of mice;Jung;Exp. Mol. Med.,2018

5. Adipocyte Metrnl Antagonizes Insulin Resistance Through PPARγ Signaling;Li;Diabetes,2015

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