Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma

Author:

Margeta Milica A.ORCID,Yin Zhuoran,Madore CharlotteORCID,Pitts Kristen M.ORCID,Letcher Sophia M.,Tang Jing,Jiang Shuhong,Gauthier Christian D.ORCID,Silveira Sebastian R.ORCID,Schroeder Caitlin M.,Lad Eleonora M.ORCID,Proia Alan D.,Tanzi Rudolph E.,Holtzman David M.,Krasemann SusanneORCID,Chen Dong FengORCID,Butovsky Oleg

Publisher

Elsevier BV

Subject

Infectious Diseases,Immunology,Immunology and Allergy

Reference101 articles.

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2. The P2X7 receptor primes IL-1beta and the NLRP3 inflammasome in astrocytes exposed to mechanical strain;Albalawi;Front. Cell. Neurosci.,2017

3. Neuroprotection in glaucoma: animal models and clinical trials;Almasieh;Annu. Rev. Vis. Sci.,2017

4. All roads lead to glaucoma: induced retinal injury cascades contribute to a common neurodegenerative outcome;Alqawlaq;Exp. Eye Res.,2019

5. GpnmbR150X allele must be present in bone marrow derived cells to mediate DBA/2J glaucoma;Anderson;BMC Genet,2008

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