Glycan Masking Focuses Immune Responses to the HIV-1 CD4-Binding Site and Enhances Elicitation of VRC01-Class Precursor Antibodies-Reference-Cited by-同舟云学术

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Glycan Masking Focuses Immune Responses to the HIV-1 CD4-Binding Site and Enhances Elicitation of VRC01-Class Precursor Antibodies

Published:2018-08 Issue:2 Volume:49 Page:301-311.e5
ISSN:1074-7613
Container-title:Immunity
language:en
Short-container-title:Immunity

Author:

Duan Hongying,Chen Xuejun,Boyington Jeffrey C.,Cheng Cheng,Zhang Yi,Jafari Alexander J.,Stephens Tyler,Tsybovsky Yaroslav,Kalyuzhniy Oleksandr,Zhao Peng,Menis Sergey,Nason Martha C.,Normandin Erica,Mukhamedova Maryam,DeKosky Brandon J.,Wells Lance,Schief William R.,Tian Ming,Alt Frederick W.,Kwong Peter D.,Mascola John R.

Funder

Vaccine Research Center, NIAID, NIH

Frederick National Laboratory for Cancer Research, National Institutes of Health

NIAID

NIGMS

United States Agency for International Development

Ministry of Foreign Affairs of the Netherlands

Bill & Melinda Gates Foundation

Publisher

Elsevier BV

Subject

Infectious Diseases,Immunology,Immunology and Allergy

Reference64 articles.

1. Precursor frequency and affinity determine B cell competitive fitness in germinal centers, tested with germline-targeting HIV vaccine immunogens;Abbott;Immunity,2018

2. An engineered mutant of HIV-1 gp120 formulated with adjuvant Quil A promotes elicitation of antibody responses overlapping the CD4-binding site;Ahmed;Vaccine,2012

3. Tailored immunogens direct affinity maturation toward HIV neutralizing antibodies;Briney;Cell,2016

4. Broadly neutralizing antibodies to HIV and their role in vaccine design;Burton;Annu. Rev. Immunol.,2016

5. RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development;Chen;Proc. Natl. Acad. Sci. USA,1993

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