Phase II study of the amsacrine analogue CI-921 (NSC 343499) in non-small cell lung cancer

Author:

Harvey Vernon J.,Hardy Janet R.,Smith Shelba,Grove William,Baguley Bruce C.

Publisher

Elsevier BV

Subject

Oncology

Reference19 articles.

1. Synthesis, antitumour activity, and DNA binding properties of a new derivative of amsacrine, N-5-dimethyl-9-[(2-methoxy-4-methylsulfonylamino) phenylamino] -4-acridinecarboxamide;Baguley;Cancer Res,1984

2. Topoisomerase II-mediated DNA damage produced by 4′-(9-acridinylamino)methanesulfon-m-anisidide and related acridines in L1210 cells and isolated nuclei: relation to cytotoxicity;Covey;Cancer Res,1988

3. Cell line selectivity and DNA breakage properties of the antitumour agent N-[2-(dimethyl-amino)ethyl]-acridine-4-carboxamide: role of DNA topoisomerase II;Schneider;Eur J Cancer Clin Oncol,1988

4. Comparison of the cytotoxicity of amsacrine and its analogue CI-921 against cultured human and mouse bone marrow tumour cells;Ching;Eur J Cancer,1990

5. Comparison of in vitro activity of cytotoxic drugs toward human carcinoma and leukaemia cell lines;Finlay;Eur J Cancer Clin Oncol,1986

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