A phase I clinical and pharmacokinetic study of brequinar sodium, DUP 785 (NSC 368390), using a weekly and a biweekly schedule

Author:

Bork E.,Vest S.,Hansen H.H.

Publisher

Elsevier BV

Subject

Oncology

Reference15 articles.

1. Activity of a novel 4-quinolinecarboxylic acid, NSC 368390 [6-fluoro-2-(2′-fluoro-1,1′-biphenyl-4-yl)-3-methyl-4-quinolinecarboxylic acid sodium salt] against experimental tumors;Dexter;Cancer Res,1985

2. Mechanism of action of the novel anticancer agent 6-fluoro-2-(2′-fluoro-1,1′-biphenyl-4-yl)-3-methyl-4-quinolinecarboxylic acid sodium salt (NSC 368390): inhibition of de novo pyrimidine nucleotide biosynthesis;Chen;Cancer Res,1986

3. Inhibition of pyrimidine de novo synthesis by DUP-785 (NSC 368390);Peters;Invest New Drugs,1987

4. Roed H, Vindeløv L, Jensen PB, Christensen IJ, Hansen HH. In vitro evaluation of a novel 4-quinolinecarboxylic acid, DUP-785 (NSC 368 390) against human small cell lung cancer cell lines. Eur J Cancer Clin Oncol (submitted).

5. Phase I study of DUP-785 (NSC 368390) in solid tumors;Joggi,1988

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