Disposition, pharmacokinetics, and metabolism of 14C-fotemustine in cancer patients

Author:

Ings R.M.J.,Gray A.J.,Taylor A.R.,Gordon B.H.,Breen M.,Hiley M.,Brownsill R.,Marchant N.,Richards R.,Wallace D.,Hughes T.,Thomas R.,Williams J.,Lucas C.,Campbell D.B.

Publisher

Elsevier BV

Subject

Oncology

Reference11 articles.

1. Phase I clinical study of the new amino acid-linked nitrosourea, S10036, administered on a weekly schedule;Khayat;Cancer Res,1987

2. Quantitative assessment of hepatic function by breath analysis after oral administration of 14C-aminopyrine;Hepner;Ann Intern Med,1975

3. A comparison of numerical integrating algorithms by trapezoid, lagrange and spline approximations;Yeh;J Pharmacokinet Biopharm,1978

4. A new method for the measurement of nitrosoureas in plasma: an h.p.l.c. method for the measurement of fotemustine kinetics;Gordon;Xenobiotica,1989

5. Main metabolite of 1-(2-chloroethyl-3-[1′-(5-p-nitrobenzoyl-2′-3′-isopropylidene)-α,β-D-ribofuranosyl-]-1-nitrosourea and 1-(2-chloroethyl)-3-(2′,3′,4′-Tri-O-acetyl-α,β-D-ribofuranosyl)-1-nitrosourea in rats;Madelmont;Drug Metab Dispos,1982

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