Bantu Tanzanians have a decreased capacity to metabolize omeprazole and mephenytoin in relation to their CYP2C19 genotype*-Reference-Cited by-同舟云学术

Bantu Tanzanians have a decreased capacity to metabolize omeprazole and mephenytoin in relation to their CYP2C19 genotype*

Published:1998-10 Issue:4 Volume:64 Page:391-401
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:
Short-container-title:Clin Pharmacol Ther

Author:

Herrlin Karin,Massele Amos Y.,Jande Mary,Alm Christina,Tybring Gunnel,Abdi Yakoub Aden,Wennerholm Agneta,Johansson Inger,Dahl Marja-Liisa,Bertilsson Leif,Gustafsson Lars L.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference46 articles.

1. Geographical/Interracial Differences in Polymorphic Drug Oxidation

2. Slow Omeprazole Metabolizers Are Also Poor S-Mephenytoin Hydroxylators

3. The activation of the biguanide antimalarial proguanil co-segregates with the mephenytoin oxidation polymorphism-a panel study.

4. Importance of genetic factors in the regulation of diazepam metabolism: Relationship to S-mephenytoin, but not debrisoquin, hydroxylation phenotype

5. The mephenytoin oxidation polymorphism is partially responsible for the N-demethylation of imipramine

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