(R)-3-(6-chloro-1-isopropylbenzimidazole-4-carboxamido)quinuclidine: A high affinity ligand for the (R)-zacopride binding site-Reference-Cited by-同舟云学术

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(R)-3-(6-chloro-1-isopropylbenzimidazole-4-carboxamido)quinuclidine: A high affinity ligand for the (R)-zacopride binding site

Published:1996-02 Issue:4 Volume:6 Page:477-480
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Flippin L.A.,Carter D.S.,Berger J.,Clark R.D.,Bonhaus D.W.,Leung E.,Eglen R.M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference10 articles.

1. Antagonism of [3H]zacopride binding to 5-HT3 recognition sites by its (R) and (S) enantiomers

2. The (S)-isomer of [3H]zacopride labels 5-HT3 receptors with high affinity in rat brain

3. Characterization of 5-HT3 and ‘atypical’ 5-HT receptors mediating guinea-pig ileal contractions in vitro

4. The potent 5-HT3 receptor antagonist (R)-zacopride labels an additional high affinity site in the central nervous system

5. Characterisation of the non-5-HT3 high-affinity ‘R’ binding site for (R)-zacopride in brain and other tissues

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1. Acid/Base-Steered Cascade Cyclization: An Efficient One-Pot Access to Diverse Isobenzofuranone and Isoindolobenzoxazinone Derivatives;Molecules;2023-02-02

2. ChemInform Abstract: (R)-3-(6-Chloro-1-isopropylbenzimidazole-4-carboxamido)quinuclidine: A High Affinity Ligand for the (R)-Zacopride Binding Site.;ChemInform;2010-08-05

3. Unexpected rearrangement of enantiomerically pure 3-aminoquinuclidine as a simple way of preparing diastereomeric octahydropyrrolo[2,3-c]pyridine derivatives;Chirality;2009-07

4. Novel Angular Benzophenazines: Dual Topoisomerase I and Topoisomerase II Inhibitors as Potential Anticancer Agents;Journal of Medicinal Chemistry;2002-01-01

5. Cross-coupling reactions in Cinchona alkaloid chemistry: aryl-substituted and dimeric quinine, quinidine, as well as quincorine and quincoridine derivatives;Journal of the Chemical Society, Perkin Transactions 1;2001

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