Synthesis and resolution of β-(aminomethyl)-4-chlorobenzeneethanesulfinic acid a potent gabaB receptor ligand-Reference-Cited by-同舟云学术

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Synthesis and resolution of β-(aminomethyl)-4-chlorobenzeneethanesulfinic acid a potent gabaB receptor ligand

Published:1995-02 Issue:3 Volume:5 Page:237-240
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Carruthers Nicholas I.,Spitler James M.,Shing-Chun Wong ,Blythin David J.,Xiao Chen ,Ho-Jane Shue ,Mittelman Stanley

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. GABA synaptic mechanisms: Stereochemical and conformational requirements

2. (–)Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor

3. 3H-baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brain

4. GABAB receptors and their significance in mammalian pharmacology

5. Dingwall, J G.; Ehrenfreund, J.; Hall, R. G.; Jack, J. USP 4 656 298, 1987.

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4. ChemInform Abstract: Synthesis and Resolution of β-(Aminomethyl)-4- chlorobenzeneethanesulfinic Acid - a Potent GABAB Receptor Ligand.;ChemInform;2010-08-17

5. Effects of (2R )-(3-amino-2-fluoropropyl)sulphinic acid (AFPSiA) on transient lower oesophageal sphincter relaxation in dogs and mechanism of hypothermic effects in mice;British Journal of Pharmacology;2005-09

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