Interaction of clofibrate with cyclodextrin in solution: phase solubility, 1H NMR and molecular modelling studies

Author:

Anguiano-Igea S.,Otero-Espinar F.J.,Vila-Jato J.L.,Blanco-Méndez J.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference28 articles.

1. Anguiano-Igea, S., Otero-Espinar, F.J., Vila-Jato, J.L. and Blanco-Méndez, J. (1996) Improvement of clofibrate dissolution by complexation with cyclodextrin. Int. J. Pharm. 135, 161–166.

2. Ben-Amor, A-F. (1990) Avantages et limites des procédés galéniques destinés à améliorer la biodisponibilité d'un principe actif peu soluble et administré par voie orale: le fénofibrate. PhD Thesis, University of Geneve.

3. Bettinetti, G.P., Mura, P., Melani, F., Giordano, F. and Setti, M. (1990) (S)-(+)-6-methoxy-α-methyl-2-naphthalene acetic acid and β-cyclodextrin derivatives, inclusion in aqueous media and solid phase interaction. In: Duchêne, D. (Editor) Minutes 5th International Symposium on Cyclodextrins. Editions de Santé, Paris, pp 239–242.

4. Blanco, J., Vila-Jato, J.L., Otero, F.J. and Anguiano, S. (1991) Influence of method of preparation on inclusion complexes of naproxen with different cyclodextrins. Drug Dev. Ind. Pharm. 17, 943–957.

5. Cabral-Marques, H.M., Hadgraft, J., Kellaway, I.W. and Pugh, W.J. (1990) Studies of cyclodextrin inclusion complexes II. Molecular modelling and 1H-NMR evidence for the salbutamol-ß-cyclodextrin complex. Int. J. Pharm. 63, 267–274.

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