Selective whole-cell biosynthesis of the designer drug metabolites 15- or 16-betahydroxynorethisterone by engineered Cytochrome P450 BM3 mutants-Reference-Cited by-同舟云学术

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Selective whole-cell biosynthesis of the designer drug metabolites 15- or 16-betahydroxynorethisterone by engineered Cytochrome P450 BM3 mutants

Published:2015-11 Issue: Volume:121 Page:64-74
ISSN:1381-1177
Container-title:Journal of Molecular Catalysis B: Enzymatic
language:en
Short-container-title:Journal of Molecular Catalysis B: Enzymatic

Author:

Reinen Jelle,Vredenburg Galvin,Klaering Karoline,Vermeulen Nico P.E.,Commandeur Jan N.M.,Honing Maarten,Vos J. Chris

Funder

Dutch Top Institute Pharma

Publisher

Elsevier BV

Subject

Process Chemistry and Technology,Biochemistry,Bioengineering,Catalysis

Reference66 articles.

1. Engineering and application of P450 monooxygenases in pharmaceutical and metabolite synthesis

2. The Evolution of Cytochrome P450 Enzymes as Biocatalysts in Drug Discovery and Development

3. Cytochrome P450 monooxygenases: an update on perspectives for synthetic application

4. Cytochrome P450: Structure, Mechanism and Biochemistry;Guengerich,2015

5. Cytochrome P450s and other enzymes in drug metabolism and toxicity

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1. Choose Your Own Adventure: A Comprehensive Database of Reactions Catalyzed by Cytochrome P450 BM3 Variants;ACS Catalysis;2024-03-29

2. Biotransformation of norethisterone by Rhizopus microsporus PT2906;Phytochemistry Letters;2023-12

3. A Promiscuous Bacterial P450: The Unparalleled Diversity of BM3 in Pharmaceutical Metabolism;International Journal of Molecular Sciences;2021-10-21

4. Hemoprotein Catalyzed Oxygenations: P450s, UPOs, and Progress toward Scalable Reactions;JACS Au;2021-07-26

5. The Recent Developments of Enzymatic Oxidation;Green Oxidation in Organic Synthesis;2019-07-12

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