Length of Uninterrupted CAG, Independent of Polyglutamine Size, Results in Increased Somatic Instability, Hastening Onset of Huntington Disease-Reference-Cited by-同舟云学术

Length of Uninterrupted CAG, Independent of Polyglutamine Size, Results in Increased Somatic Instability, Hastening Onset of Huntington Disease

Published:2019-06 Issue:6 Volume:104 Page:1116-1126
ISSN:0002-9297
Container-title:The American Journal of Human Genetics
language:en
Short-container-title:The American Journal of Human Genetics

Author:

Wright Galen E.B.,Collins Jennifer A.,Kay Chris,McDonald Cassandra,Dolzhenko Egor,Xia Qingwen,Bečanović Kristina,Drögemöller Britt I.,Semaka Alicia,Nguyen Charlotte M.,Trost Brett,Richards Fiona,Bijlsma Emilia K.,Squitieri Ferdinando,Ross Colin J.D.,Scherer Stephen W.,Eberle Michael A.,Yuen Ryan K.C.,Hayden Michael R.

Funder

Canadian Institutes of Health Research

Publisher

Elsevier BV

Subject

Genetics (clinical),Genetics

Reference35 articles.

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2. Huntington disease reduced penetrance alleles occur at high frequency in the general population;Kay;Neurology,2016

3. New problems in testing for Huntington’s disease: the issue of intermediate and reduced penetrance alleles;Maat-Kievit;J. Med. Genet.,2001

4. A new model for prediction of the age of onset and penetrance for Huntington’s disease based on CAG length;Langbehn;Clin. Genet.,2004

5. Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington’s disease age of onset;Wexler;Proc. Natl. Acad. Sci. USA,2004

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