Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy

Author:

Lesage Suzanne,Drouet Valérie,Majounie Elisa,Deramecourt Vincent,Jacoupy Maxime,Nicolas Aude,Cormier-Dequaire Florence,Hassoun Sidi Mohamed,Pujol Claire,Ciura Sorana,Erpapazoglou Zoi,Usenko Tatiana,Maurage Claude-Alain,Sahbatou Mourad,Liebau Stefan,Ding Jinhui,Bilgic Basar,Emre Murat,Erginel-Unaltuna Nihan,Guven Gamze,Tison François,Tranchant Christine,Vidailhet Marie,Corvol Jean-Christophe,Krack Paul,Leutenegger Anne-Louise,Nalls Michael A.,Hernandez Dena G.,Heutink Peter,Gibbs J. Raphael,Hardy John,Wood Nicholas W.,Gasser Thomas,Durr Alexandra,Deleuze Jean-François,Tazir Meriem,Destée Alain,Lohmann Ebba,Kabashi Edor,Singleton Andrew,Corti Olga,Brice Alexis,Lesage Suzanne,Tison François,Vidailhet Marie,Corvol Jean-Christophe,Agid Yves,Anheim Mathieu,Bonnet Anne-Marie,Borg Michel,Broussolle Emmanuel,Damier Philippe,Destée Alain,Dürr Alexandra,Durif Franck,Krack Paul,Klebe Stephan,Lohmann Ebba,Martinez Maria,Pollak Pierre,Rascol Olivier,Tranchant Christine,Vérin Marc,Viallet François,Brice Alexis,Lesage Suzanne,Majounie Elisa,Tison François,Vidailhet Marie,Corvol Jean Christophe,Nalls Michael A.,Hernandez Dena G.,Gibbs J. Raphael,Dürr Alexandra,Arepalli Sampath,Barker Roger A.,Ben-Shlomo Yoav,Berg Daniela,Bettella Francesco,Bhatia Kailash,de Bie Rob M.A.,Biffi Alessandro,Bloem Bastiaan R.,Bochdanovits Zoltan,Bonin Michael,Lesage Suzanne,Tison François,Vidailhet Marie,Corvol Jean-Christophe,Agid Yves,Anheim Mathieu,Bonnet Anne-Marie,Borg Michel,Broussolle Emmanuel,Damier Philippe,Destée Alain,Dürr Alexandra,Durif Franck,Krack Paul,Klebe Stephan,Lohmann Ebba,Martinez Maria,Pollak Pierre,Rascol Olivier,Tranchant Christine,Vérin Marc,Bras Jose M.,Brockmann Kathrin,Brooks Janet,Burn David J.,Charlesworth Gavin,Chen Honglei,Chinnery Patrick F.,Chong Sean,Clarke Carl E.,Cookson Mark R.,Counsell Carl,Damier Philippe,Dartigues Jean-François,Deloukas Panos,Deuschl Günther,Dexter David T.,van Dijk Karin D.,Dillman Allissa,Dong Jing,Durif Frank,Edkins Sarah,Escott-Price Valentina,Evans Jonathan R.,Foltynie Thomas,Gao Jianjun,Gardner Michelle,Goate Alison,Gray Emma,Guerreiro Rita,Harris Clare,van Hilten Jacobus J.,Hofman Albert,Hollenbeck Albert,Holmans Peter,Holton Janice,Hu Michèle,Huang Xuemei,Huber Heiko,Hudson Gavin,Hunt Sarah E.,Huttenlocher Johanna,Illig Thomas,Jónsson Pálmi V.,Kilarski Laura L.,Jansen Iris E.,Lambert Jean-Charles,Langford Cordelia,Lees Andrew,Lichtner Peter,Limousin Patricia,Lopez Grisel,Lorenz Delia,Lubbe Steven,Lungu Codrin,Martinez María,Mätzler Walter,McNeill Alisdair,Moorby Catriona,Moore Matthew,Morrison Karen E.,Mudanohwo Ese,O’Sullivan Sean S.,Owen Michael J.,Pearson Justin,Perlmutter Joel S.,Pétursson Hjörvar,Plagnol Vincent,Pollak Pierre,Post Bart,Potter Simon,Ravina Bernard,Revesz Tamas,Riess Olaf,Rivadeneira Fernando,Rizzu Patrizia,Ryten Mina,Saad Mohamad,Simón-Sánchez Javier,Sawcer Stephen,Schapira Anthony,Scheffer Hans,Schulte Claudia,Sharma Manu,Shaw Karen,Sheerin Una-Marie,Shoulson Ira,Shulman Joshua,Sidransky Ellen,Spencer Chris C.A.,Stefánsson Hreinn,Stefánsson Kári,Stockton Joanna D.,Strange Amy,Talbot Kevin,Tanner Carlie M.,Tashakkori-Ghanbaria Avazeh,Trabzuni Daniah,Traynor Bryan J.,Uitterlinden André G.,Velseboer Daan,Walker Robert,van de Warrenburg Bart,Wickremaratchi Mirdhu,Williams-Gray Caroline H.,Winder-Rhodes Sophie,Wurster Isabel,Williams Nigel,Morris Huw R.,Heutink Peter,Hardy John,Wood Nicholas W.,Gasser Thomas,Singleton Andrew B.,Brice Alexis

Funder

Lille brain bank

National Research Funding Agency

ERA-NET NEURON

France-Parkinson Association

Roger de Spoelberch Foundation

French Academy of Sciences

the French program “Investissements d’avenir”

European Joint Programme - Neurodegenerative Disease Research

National Institute on Aging

National Institutes of Neurological Disorders and Stroke

NIH

Department of Health and Human Services

MRC

European Social Fund

Ministry of Science, Research, and the Arts

Baden-Württemberg

Department of Defense

French Health Ministry

France Parkinson Association

Lille University Hospital

National Institute of Health and Medical Research

ERA-NET E-rare program

France Alzheimer Association

Marie Curie Actions

Cognacq-Jay Foundation

EMBO

AFM-Telethon

Publisher

Elsevier BV

Subject

Genetics(clinical),Genetics

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