Whole-Genome-Sequence-Based Haplotypes Reveal Single Origin of the Sickle Allele during the Holocene Wet Phase

Author:

Shriner Daniel,Rotimi Charles N.

Funder

Center for Research on Genomics and Global Health

National Human Genome Research Institute

National Institute of Diabetes and Digestive and Kidney Diseases

Center for Information Technology

Office of the Director at the National Institutes of Health

Publisher

Elsevier BV

Subject

Genetics (clinical),Genetics

Reference54 articles.

1. Haplotype diversity and linkage disequilibrium at human G6PD: recent origin of alleles that confer malarial resistance;Tishkoff;Science,2001

2. Evolutionary and historical aspects of the burden of malaria;Carter;Clin. Microbiol. Rev.,2002

3. Origin of the β S-globin gene in Blacks: the contribution of recurrent mutation or gene conversion or both;Antonarakis;Proc. Natl. Acad. Sci. USA,1984

4. Evidence for the multicentric origin of the sickle cell hemoglobin gene in Africa;Pagnier;Proc. Natl. Acad. Sci. USA,1984

5. Geographical survey of β S-globin gene haplotypes: evidence for an independent Asian origin of the sickle-cell mutation;Kulozik;Am. J. Hum. Genet.,1986

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