Unacylated ghrelin stimulates fatty acid oxidation to protect skeletal muscle against palmitate-induced impairment of insulin action in lean but not high-fat fed rats-Reference-Cited by-同舟云学术

Unacylated ghrelin stimulates fatty acid oxidation to protect skeletal muscle against palmitate-induced impairment of insulin action in lean but not high-fat fed rats

Published:2020-03 Issue: Volume:5 Page:100026
ISSN:2589-9368
Container-title:Metabolism Open
language:en
Short-container-title:Metabolism Open

Author:

Cervone Daniel T.,Hucik Barbora,Lovell Andrew J.^ORCID,Dyck David J.

Funder

Natural Sciences and Engineering Research Council (NSERC) of Canada

NSERC Post-Graduate Doctoral Scholarship

Publisher

Elsevier BV

Subject

General Medicine

Reference44 articles.

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2. Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity;Gauna;J Clin Endocrinol Metab,2004

3. Ghrelin infusion in humans induces acute insulin resistance and lipolysis independent of growth hormone signaling;Vestergaard;Diabetes,2008

4. Acute effects of ghrelin administration on glucose and lipid metabolism;Vestergaard;J Clin Endocrinol Metab,2008

5. Unacylated ghrelin reduces skeletal muscle reactive oxygen species generation and in fl ammation and prevents high-fat diet – induced hyperglycemia and whole-body insulin resistance in rodents;Cappellari;Diabetes,2016

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2. Stimulation of fat oxidation in rat muscle by unacylated ghrelin persists for 2–3 hours, but is independent of fatty acid transporter translocation;Physiological Reports;2023-09

3. Exogenous administration of unacylated ghrelin attenuates hepatic steatosis in high-fat diet-fed rats by modulating glucose homeostasis, lipogenesis, oxidative stress, and endoplasmic reticulum stress;Biomedicine & Pharmacotherapy;2022-07

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5. Ghrelin is a signal to facilitate the utilization of fatty acids and save glucose by the liver, skeletal muscle, and adipose tissues in chicks;Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids;2022-02