Structural dynamics and kinase inhibitory activity of three generations of tyrosine kinase inhibitors against wild-type, L858R/T790M, and L858R/T790M/C797S forms of EGFR
Author:
Publisher
Elsevier BV
Subject
Health Informatics,Computer Science Applications
Reference105 articles.
1. Osimertinib making a breakthrough in lung cancer targeted therapy;Zhang;OncoTargets Ther.,2016
2. Epidermal growth factor receptor (EGFR) in lung cancer: an overview and update;Bethune;J. Thorac. Dis.,2010
3. Shikonin inhibits gefitinib-resistant non-small cell lung cancer by inhibiting TrxR and activating the EGFR proteasomal degradation pathway;Li;Pharmacol. Res.,2017
4. Targeting drug resistance in EGFR with covalent inhibitors: a structure-based design approach;Engel;J. Med. Chem.,2015
5. Oral epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of non-small cell lung cancer: comparative pharmacokinetics and drug–drug interactions;Peters;Cancer Treat Rev.,2014
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