Omics-based identification of an NRF2-related auranofin resistance signature in cancer: Insights into drug repurposing

Author:

Falchetti Marcelo,Delgobo MarinaORCID,Zancanaro Helena,Almeida Karoline,das Neves Raquel NascimentoORCID,dos Santos Barbara,Stefanes Natália Marcéli,Bishop Alexander,Santos-Silva Maria Cláudia,Zanotto-Filho AlfeuORCID

Funder

Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Elsevier BV

Subject

Health Informatics,Computer Science Applications

Reference68 articles.

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3. Selective inhibition of endogenous antioxidants with Auranofin causes mitochondrial oxidative stress which can be countered by selenium supplementation;Radenkovic;Biochem. Pharmacol.,2017

4. Reactive oxygen species, antioxidants, and the mammalian thioredoxin system;Nordberg;Free Radic. Biol. Med.,2001

5. TrxR1 as a potent regulator of the Nrf2-Keap1 response system;Cebula;Antioxidants Redox Signal.,2015

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