In-silico evidences for binding of Glucokinase activators to EGFR C797S to overcome EGFR resistance obstacle with mutant-selective allosteric inhibition-Reference-Cited by-同舟云学术

In-silico evidences for binding of Glucokinase activators to EGFR C797S to overcome EGFR resistance obstacle with mutant-selective allosteric inhibition

Published:2018-06 Issue: Volume:74 Page:167-189
ISSN:1476-9271
Container-title:Computational Biology and Chemistry
language:en
Short-container-title:Computational Biology and Chemistry

Author:

Patel Harun,Pawara Rahul,Surana Sanjay

Funder

Science and Engineering Research Board (SERB) of Department of Science and Technology (DST) Govt. of India

Publisher

Elsevier BV

Subject

Computational Mathematics,Organic Chemistry,Biochemistry,Structural Biology

Reference61 articles.

1. Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer;Amann;Cancer Res.,2005

2. Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog;Boggon;Blood,2005

3. Acquired resistance to TKIs in solid tumours: learning from lung cancer;Camidge;Nat. Rev. Clin. Oncol.,2014

4. Kinetic analysis of epidermal growth factor receptor somatic mutant proteins shows increased sensitivity to the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib;Carey;Cancer Res.,2006

5. Mutations of the epidermal growth factor receptor in non-small cell lung cancer: search and destroy;Chan;Eur. J. Cancer,2006

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Ligand and structure-based virtual screening approaches in drug discovery: minireview;Molecular Diversity;2024-09-02

2. Exploring the structural activity relationship of the Osimertinib: A covalent inhibitor of double mutant EGFRL858R/T790M tyrosine kinase for the treatment of Non-Small Cell Lung Cancer (NSCLC);Bioorganic & Medicinal Chemistry;2024-07

3. Design, Synthesis, and Biological Evaluation of Dual Inhibitors of EGFR^L858R/T790M/ACK1 to Overcome Osimertinib Resistance in Nonsmall Cell Lung Cancers;Journal of Medicinal Chemistry;2024-02-07

4. Synthesis and Anticancer Activity of Novel Derivatives of α,β‐Unsaturated Ketones Based on Oleanolic Acid: in Vitro and in Silico Studies against Prostate Cancer Cells;Chemistry & Biodiversity;2023-09

5. Assessment of Binding Site and Development of Small Molecule Inhibitors Targeting Epidermal Growth Factor Receptor Mutations in Non-Small Cell Lung Cancer (NSCLC);Letters in Drug Design & Discovery;2023-09