The anabolic effect of human PTH (1–34) on bone formation is blunted when bone resorption is inhibited by the bisphosphonate tiludronate—is activated resorption a prerequisite for the in vivo effect of PTH on formation in a remodeling system?

Author:

Delmas P.D.,Vergnaud P.,Arlot M.E.,Pastoureau P.,Meunier P.J.,Nilssen M.H.L.

Publisher

Elsevier BV

Subject

Histology,Physiology,Endocrinology, Diabetes and Metabolism

Reference44 articles.

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2. Human parathyroid peptide (hPTH 1-34) treatment increases the mean wall thickness of iliac trabecular packets of new bone in patients with crush fracture osteoporosis;Bradbeer;J Bone Min Res,1988

3. Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures;Canalis;J Clin Invest,1989

4. Parathyroid hormone modulates transforming growth factor beta activity and binding in osteoblastenriched cell cultures from fetal rat parietal bone;Centrella,1988

5. Intermethod variation in bone histomorphometry: Comparison between manual and computerized methods applied to iliac bone biopsies;Chavassieux;Bone,1985

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