Preventive effect of a heparinoid-containing product on the application site reaction of the rotigotine transdermal patch in Parkinson’s disease: A pilot randomized clinical trial (the SkinHeRo study)

Author:

Koh Jinsoo,Takahashi Maiko,Sakata Mayumi,Yasui Masaaki,Yorozu Shoko,Ito Hidefumi

Funder

Japan Society for the Promotion of Science

Publisher

Elsevier BV

Subject

General Medicine

Reference12 articles.

1. Focus on depression in parkinson's disease: a delphi consensus of experts in psychiatry, neurology, and geriatrics;Agüera-Ortiz;Parkinsons Dis.,2021

2. Evaluation of rotigotine transdermal patch for the treatment of apathy and motor symptoms in Parkinson's disease;Hauser;BMC Neurol.,2016

3. Rotigotine is a potent agonist at dopamine D1 receptors as well as at dopamine D2 and D3 receptors;Wood;Br. J. Pharmacol.,2015

4. Transdermal rotigotine: double-blind, placebo-controlled trial in Parkinson disease;Jankovic;Arch. Neurol.,2007

5. A topical heparinoid-containing product improves epidermal permeability barrier homeostasis in mice;Yao;Exp. Dermatol.,2019

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