Dopamine D4 receptors bind inactive (+)-aporphines, suggesting neuroleptic role. Sulpiride not stereoselective

Author:

Seeman Philip,Van Tol Hubert H.M.

Publisher

Elsevier BV

Subject

Pharmacology

Reference7 articles.

1. Selective antidopaminergic effects of S(+)N-n-propylnoraporphines in limbic versus extrapyramidal sites in rat brain: comparisons with typical and atypical antipsychotic agents;Campbell;Psychopharmacology,1991

2. The dopamine D4 and D2 receptors: Comparison of neuroleptic binding affinities;Figur;Soc. Neurosci. Abstr.,1992

3. Inhibition or R-(−)apomorphine-induced stereotypic activity and striatal (3H)-spiroperidol and (3H)apomorphine receptor binding by S-(+)-apomorphine;Riffee;Soc. Neurosci. Abstr. 7, Abstr. 42.8,1981

4. Dopamine receptor sequences. Therapeutic levels of neuroleptics occupy D2, clozapine occupies D4;Seeman;Neuropsychopharmacology,1992

5. Dopamine D2 receptor binding sites for agonists: A tetrahedral model;Seeman;Mol. Pharmacol.,1985

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