Characterization of the novel 5-HT3 antagonists MDL 73147EF (dolasetron mesilate) and MDL 74156 in NG108-15 neuroblastoma × glioma cells

Author:

Boeijinga Peter H.,Galvan Martin,Baron Bruce M.,Dudley Mark W.,Siegel Barry W.,Slone Amy L.

Publisher

Elsevier BV

Subject

Pharmacology

Reference21 articles.

1. Characterization and autoradiographic localisation of 5-HT3 receptor recognition sites identified with [3H]-(S)-zacopride in the forebrain of the rat;Barnes;Neuropharmacology,1990

2. A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein-dye binding;Bradford;Anal. Biochem.,1976

3. 5-HT3 receptors are membrane ion channels;Derkach;Nature,1989

4. Stereo-selectivity in the reduction of MDL 73147, an achiral ketone, to a chiral alcohol in man;Dow,1991

5. Potent 5-HT3 antagonists incorporating a novel bridged pseudopelletierine ring system;Gittos;Actual Chim. Ther.,1989

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