Inhibition of calcium ionophore (A23187)-stimulated histamine release from rat peritoneal mast cells by azelastine: Implications for its mode of action

Author:

Chand Naresh,Pillar John,Diamantis William,Perhach James L.,Duane Sofia R.

Publisher

Elsevier BV

Subject

Pharmacology

Reference18 articles.

1. Inhibition of leukotriene (SRS-A)-mediated allergic bronchospasm by azelastine, a novel, orally effective antiasthmatic drug;Chand;J. Allergy Clin. Immunol.,1983

2. Inhibition of calcium ionophore (A23187)-induced histamine release by a novel antiallergic agent, 4-(p-chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepine-4yl)-1(2H)-phthalazinone hydrochloride (azelastine; A5610);Chand;Int. J. Immunopharmacol.,1982

3. Inhibition of allergic histamine secretion from rat peritoneal mast cells (RPMC) by azelastine, a novel, orally acting antiallergic agent;Chand;Pharmacologist,1983

4. Stimulation and inhibition of histamine release from isolated rat mast cells. Dual effects of the ionophore A23187;Diamant;Int. Arch. Allergy Appl. Immunol.,1975

5. Inhibition of release of SRS-A and its antagonism by azelastine (A), an H1 antagonist-antialergic agent;Diamantis;Pharmacologist,1982

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