Synthesis and pharmacology of irreversible affinity labels as potential cocaine antagonists: aryl 1,4-dialkylpiperazines related to GBR-12783

Author:

Deutsch Howard M.,Schweri Margaret M.,Culbertson Christopher T.,Zalkow Leon H.

Publisher

Elsevier BV

Subject

Pharmacology

Reference32 articles.

1. Metaphil, a receptor acylator, inactivates cocaine binding sites in striatum and antagonizes cocaine-induced locomotor stimulation in rodents;Berger;Neuropharmacology,1986

2. Photoaffinity labeling of the dopamine reuptake carrier protein with 3-azido[3H]GBR-12935;Berger;Mol. Pharmacol.,1991

3. Isothiocyanate derivatives of cocaine: irreversible inhibition of ligand binding at the dopamine transporter;Boja;Mol. Pharmacol.,1991

4. Acylating phencyclidines irreversibly enhance brain calcium antagonist binding;Bolger;Pharmacol. Biochem. Behav.,1986

5. High-affinity [3H]GBR 12783 binding to a specific site associated with the neuronal dopamine uptake complex in the central nervous system;Bonnet;Eur. J. Pharmacol.,1986

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