The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine

Author:

Berger Urs V.,Gu Xi F.,Azmitia Efrain C.

Publisher

Elsevier BV

Subject

Pharmacology

Reference46 articles.

1. Fenfluramine selectively and differentially decreases the density of serotonergic nerve terminals in rat brain: evidence from immunocytochemical studies;Appel;J. Pharmacol. Exp. Ther.,1989

2. Direct morphologic evidence for degeneration of serotonergic axons following administration of amphetamine derivatives: dl-p-chloroamphetamine, d-methamphetamine, and d- and l-fenfluramine;Axt;Soc. Neurosci. Abstr.,1990

3. MDMA (ecstasy) effects on cultures serotonergic neurons: evidence for Ca2(+)-dependent toxicity linked to release;Azmitia;Brain Res.,1990

4. 3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: Quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites;Battaglia;J. Pharmacol. Exp. Ther.,1987

5. Effects of fenfluramine on accumulation of 5-hydroxytryptamine and other neurotransmitters into synaptosomes of rat brain;Belin;Neuropharmacology,1976

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